This article is from PLoS ONE, volume 9.AbstractPurpose: The aim of the present study was to examine the biological differences between seminomas with occult and clinically apparent metastases at the time of diagnosis of the primary tumor to gain insight into the biology of these tumors and facilitate the identification of novel predictors of seminoma metastasis. Materials and Methods: Total RNA including small RNAs was isolated from testicular tumors of patients with pure seminoma presenting... Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006798
byKamm, Christian P.; El-Koussy, Marwan; Humpert, Sebastian; Findling, Oliver; Burren, Yuliya; Schwegler, Guido; Donati, Filippo; Muller, Martin; Muller, Felix; Slotboom, Johannes; Kappos, Ludwig; Naegelin, Yvonne; Mattle, Heinrich P.
This article is from PLoS ONE, volume 9.AbstractBackground: Statins have anti-inflammatory and immunomodulatory properties in addition to lipid-lowering effects. Objectives: To report the 12-month extension of a phase II trial evaluating the efficacy, safety and tolerability of atorvastatin 40 mg/d added to interferon beta-1b (IFNB-1b) in relapsing-remitting multiple sclerosis (RRMS). Methods: In the randomized, multicenter, parallel-group, rater-blinded core study, 77 RRMS patients started... Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907426